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Article

Desmosomal plakophilins in the prostate and prostatic adenocarcinomas: implications for diagnosis and tumor progression.

The American journal of pathology - 1 May 2010

Breuninger Sonja, Reidenbach Sonja, Sauer Christian Georg, Ströbel Philipp, Pfitzenmaier Jesco, Trojan Lutz, Hofmann Ilse

Abstract excerpt

The plakophilins, members of the armadillo-repeat family, consist of three different proteins (PKP1-3) that are specifically recruited to desmosomal plaques in a highly cell type-specific manner. Using immunofluorescence, immunoelectron microscopy, and immunoblot, we found that all three plakophilins occurred in luminal and basal cells of the pseudostratified prostate epithelium. The analysis of 135 cases of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20348237
DOI: 10.2353/ajpath.2010.090737
PMCID: PMC2861115

Genes

PKP3
PKP1
PKP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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