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Genetic Mutations of Pancreatic Cancer and Genetically Engineered Mouse Models

24 Dec 2021

Abstract excerpt

Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy, and the seventh leading cause of cancer-related deaths worldwide. An improved understanding of tumor biology and novel therapeutic discoveries are needed to improve overall survival. Recent multi-gene analysis approaches such as next-generation sequencing have provided useful information on the molecular characterization of pancreatic...

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PMID: 35008235
DOI: 10.3390/cancers14010071

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