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Article

Polarization of the yeast pheromone receptor requires its internalization but not actin-dependent secretion.

Molecular biology of the cell - 15 May 2010

Suchkov Dmitry V, DeFlorio Reagan, Draper Edward, Ismael Amber, Sukumar Madhushalini, Arkowitz Robert, Stone David E

Abstract excerpt

In the best understood models of eukaryotic directional sensing, chemotactic cells maintain a uniform distribution of surface receptors even when responding to chemical gradients. The yeast pheromone receptor is also uniformly distributed on the plasma membrane of vegetative cells, but pheromone induces its polarization into "crescents" that cap the future mating projection. Here, we find that in...

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Identifiers

PMID: 20335504
DOI: 10.1091/mbc.e09-08-0706
PMCID: PMC2869379

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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