Article
Yeast G-proteins mediate directional sensing and polarization behaviors in response to changes in pheromone gradient direction.
Molecular biology of the cell - 1 Feb 2013
Moore Travis I, Tanaka Hiromasa, Kim Hyung Joon, Jeon Noo Li, Yi Tau-Mu
Abstract excerpt
Yeast cells polarize by projecting up mating pheromone gradients, a classic cell polarity behavior. However, these chemical gradients may shift direction. We examine how yeast cells sense and respond to a 180(o) switch in the direction of microfluidically generated pheromone gradients. We identify two behaviors: at low concentrations of α-factor, the initial projection grows by bending, whereas at high...
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