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Article

Mitotic and pheromone-specific intrinsic polarization cues interfere with gradient sensing in Saccharomyces cerevisiae.

Proceedings of the National Academy of Sciences of the United States of America - 24 Mar 2020

Vasen Gustavo, Dunayevich Paula, Colman-Lerner Alejandro

Abstract excerpt

Polarity decisions are central to many processes, including mitosis and chemotropism. In Saccharomyces cerevisiae, budding and mating projection (MP) formation use an overlapping system of cortical landmarks that converges on the small G protein Cdc42. However, pheromone-gradient sensing must override the Rsr1-dependent internal polarity cues used for budding. Using this model system, we asked what happens when...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32152126
DOI: 10.1073/pnas.1912505117
PMCID: PMC7104260

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