Article
Short communication: selection of thymidine analogue resistance mutational patterns in children infected from a common HIV type 1 subtype G source.
AIDS research and human retroviruses - 1 Mar 2010
Däumer Martin, Awerkiew Sabine, Aragón Saleta Sierra, Kartashev Vladimir, Poplavskaja Tatjana, Klein Rolf, Sichtig Nadine, Thiele Bernhard, Lengauer Thomas, Roomp Kirsten, Pfister Herbert, Kaiser Rolf
Abstract excerpt
In HIV-1, thymidine analogue mutations (TAMs) cluster in one of two groups (215Y, 41L, 210W, or 215F, 219E/Q), representing two independent mutational patterns (T215Y and T215F cluster, respectively). The mechanisms by which these pathways are selected are not fully understood. To investigate pos...
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