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Article

Thymidine analogue mutation profiles: factors associated with acquiring specific profiles and their impact on the virological response to therapy.

Antiviral therapy - 1 Jan 2005

Cozzi-Lepri Alessandro, Ruiz Lidia, Loveday Clive, Phillips Andrew N, Clotet Bonaventura, Reiss Peter, Ledergerber Bruno, Holkmann Christian, Staszewski Schlomo, Lundgren Jens D

Abstract excerpt

BACKGROUND: Studies have suggested that HIV-1 may develop thymidine analogue mutations (TAMs) by one of two distinct pathways - the TAM1 pathway (including mutations 41L, 210W and 215Y) or the TAM2 pathway (including mutations 67N, 70R and 219E/Q) - under the pressure of a not fully suppressive thymidine-analogue-containing regimen. METHODS: Frozen plasma samples stored in the EuroSIDA repository were selected...

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PMID: 16312176

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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