Article
Mycobacterium smegmatis D-Alanine Racemase Mutants Are Not Dependent on D-Alanine for Growth.
Antimicrobial agents and chemotherapy - 1 Jan 2002
Chacon Ofelia, Feng Zhengyu, Harris N Beth, Cáceres Nancy E, Adams L Garry, Barletta Raúl G
Abstract excerpt
Mycobacterium smegmatis is a fast-growing nonpathogenic species particularly useful in studying basic cellular processes of relevance to pathogenic mycobacteria. This study focused on the D-alanine racemase gene (alrA), which is involved in the synthesis of D-alanine, a basic component of peptidoglycan that forms the backbone of the cell wall. M. smegmatis alrA null mutants were generated by homologous...
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