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Article

Sepsis in acute myeloid leukaemia patients receiving high-dose chemotherapy: no impact of chitotriosidase and mannose-binding lectin polymorphisms.

European journal of haematology - 1 Jul 2010

Klostergaard Anja, Steffensen Rudi, Møller Jens K, Peterslund Niels, Juhl-Christensen Caroline, Mølle Ingolf

Abstract excerpt

Infections after chemotherapy often cause significant morbidity in patients with acute myeloid leukaemia (AML). Chitotriosidase (CHIT) and mannose-binding lectin (MBL) are part of the innate immune system. Polymorphism in the CHIT-coding gene (CHIT1) may be associated with Gram-negative sepsis in...

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Source

Identifiers

PMID: 20331735
DOI: 10.1111/j.1600-0609.2010.01443.x

Genes

CHIT1
MBL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20331735-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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