Debrisoquine oxidation in Parkinson's disease.

doi:10.1111/j.1600-0404.1991.tb04676.x

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Article

Debrisoquine oxidation in Parkinson's disease.

Acta neurologica Scandinavica - 1 Mar 1991

Kallio J, Marttila R J, Rinne U K, Sonninen V, Syvälahti E

Abstract excerpt

Variations in the activities of xenobiotic metabolizing liver enzymes may be involved in the pathophysiology of diseases, including Parkinson's disease. We therefore studied the activity of the debrisoquine metabolizing enzyme in 97 patients with newly diagnosed Parkinson's disease. The urine deb...

Topics

Adult
Aged
Aged, 80 and over
Cytochrome P-450 CYP2D6
Cytochrome P-450 Enzyme System
Debrisoquin
Female
Humans
Male
Middle Aged
Mixed Function Oxygenases
Parkinson Disease
Phenotype

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