Article
Debrisoquine oxidation in Parkinson's disease.
Acta neurologica Scandinavica - 1 Mar 1991
Kallio J, Marttila R J, Rinne U K, Sonninen V, Syvälahti E
Abstract excerpt
Variations in the activities of xenobiotic metabolizing liver enzymes may be involved in the pathophysiology of diseases, including Parkinson's disease. We therefore studied the activity of the debrisoquine metabolizing enzyme in 97 patients with newly diagnosed Parkinson's disease. The urine debrisoquine metabolic ratios (MR) of the patients were compared with a group of 176 healthy subjects. There were 4 poor...
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