Article
Debrisoquine hydroxylase and Parkinson's disease.
Advances in neurology - 1 Jan 1993
Kondo I, Kanazawa I
Abstract excerpt
The relationship between the genotypes of Xba I and Bam H I restriction fragment length polymorphisms (RFLPs) at a gene for debrisoquine hydroxylase (CYP2D6) and phenotypes of the metabolic function of debrisoquine/sparteine, the EM and the PM in a healthy Japanese population was investigated. Th...
Topics
- Autoradiography
- Chromosome Aberrations
- Chromosome Disorders
- Cloning, Molecular
- Cytochrome P-450 CYP2D6
- Cytochrome P-450 Enzyme System
- Genes, Recessive
- Genetics, Population
- Genotype
- Humans
- Japan
- Mixed Function Oxygenases
- Parkinson Disease
- Phenotype
- Risk Factors
- Sparteine