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Article

Cellular mechanisms of redox cell signalling: role of cysteine modification in controlling antioxidant defences in response to electrophilic lipid oxidation products.

The Biochemical journal - 1 Mar 2004

Levonen Anna-Liisa, Landar Aimee, Ramachandran Anup, Ceaser Erin K, Dickinson Dale A, Zanoni Giuseppe, Morrow Jason D, Darley-Usmar Victor M

Abstract excerpt

The molecular mechanisms through which oxidized lipids and their electrophilic decomposition products mediate redox cell signalling is not well understood and may involve direct modification of signal-transduction proteins or the secondary production of reactive oxygen or nitrogen species in the cell. Critical in the adaptation of cells to oxidative stress, including exposure to subtoxic concentrations of...

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Identifiers

PMID: 14616092
DOI: 10.1042/BJ20031049
PMCID: PMC1223973

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