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Article

ACB-PCR quantification of K-RAS codon 12 GAT and GTT mutant fraction in colon tumor and non-tumor tissue.

Cancer investigation - 1 May 2010

Parsons Barbara L, Marchant-Miros Kathryn E, Delongchamp Robert R, Verkler Tracie L, Patterson Tucker A, McKinzie Page B, Kim Lawrence T

Abstract excerpt

K-RAS mutation is being developed as a cancer biomarker and tumor K-RAS is being used to predict therapeutic response. Yet, levels of K-RAS mutation in normal and pathological tissue samples have not been determined rigorously, nor inter-individual variation in these levels characterized. Therefore, K-RAS codon 12 GAT and GTT mutant fractions were measured in colonic mucosa of individuals without colon cancer,...

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Identifiers

PMID: 20307197
DOI: 10.3109/07357901003630975

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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