Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The 3D8 single chain variable fragment protein suppresses Newcastle disease virus transmission in transgenic chickens

6 Aug 2020

Abstract excerpt

Abstract Background The 3D8 single chain variable fragment (scFv) is a mini-antibody sequence that exhibits independent nuclease activity against all types of nucleic acids. In this research, crossing a 3D8 scFv G1 transgenic rooster with wild-type hens produced 3D8 scFv G2 transgenic chickens to evaluate suppression of viral transmission. Result The transgenic chickens were identified using genomic PCR and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animal Genetics and Reproduction
Share to Virology and Viral Diseases
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32762754
DOI: 10.1186/s12917-020-02462-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The 3D8 single chain variable fragment protein suppresses Newcastle disease virus transmission in transgenic chickensPMID 32762754Read ↗

User-Friendly Reverse Genetics System for Modification of the Right End of Fowl Adenovirus 4 GenomeSemantic proximity Read ↗

Consistent production of transgenic chickens using replication-deficient retroviral vectors and high-throughput screening procedures.Semantic proximity Read ↗

Chickens Expressing IFIT5 Ameliorate Clinical Outcome and Pathology of Highly Pathogenic Avian Influenza and Velogenic Newcastle Disease VirusesSemantic proximity Read ↗

Protective efficacy in chickens, geese and ducks of an H5N1-inactivated vaccine developed by reverse geneticsSemantic proximity Read ↗

Transcriptome Analysis Reveals Inhibitory Effects of Lentogenic Newcastle Disease Virus on Cell Survival and Immune Function in Spleen of Commercial Layer ChicksSemantic proximity Read ↗

Newcastle Disease Virus as a Vaccine Vector for 20 Years: A Focus on Maternally Derived Antibody InterferenceSemantic proximity Read ↗

A Genetically Engineered Commercial Chicken Line Is Resistant to Highly Pathogenic Avian Leukosis Virus Subgroup JSemantic proximity Read ↗

Neutralization Analysis of a Chicken Single-Chain Variable Fragment Derived from an Immune Antibody Library Against Infectious Bronchitis Virus.Semantic proximity Read ↗

In Vivo Inhibition of Marek’s Disease Virus in Transgenic Chickens Expressing Cas9 and gRNA against ICP4Semantic proximity Read ↗

Development of a novel thermostable Newcastle disease virus vaccine vector for expression of a heterologous geneSemantic proximity Read ↗

Genetic Modification of Oncolytic Newcastle Disease Virus for Cancer TherapySemantic proximity Read ↗

Construction and immune efficacy of a recombinant turkey herpesvirus vaccine strain expressing fusion protein of genotype VII Newcastle disease virus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.