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Article

Genetic variation in human HBB is associated with Plasmodium falciparum transmission.

Nature genetics - 1 Apr 2010

Gouagna Louis Clement, Bancone Germana, Yao Frank, Yameogo Bienvenue, Dabiré Kounbobr Roch, Costantini Carlo, Simporé Jacques, Ouedraogo Jean Bosco, Modiano David

Abstract excerpt

Genetic factors are known to have a role in determining susceptibility to infectious diseases, although it is unclear whether they may also influence host efficiency in transmitting pathogens. We examine variants in HBB that have been shown to be protective against malaria and test whether these are associated with the transmission of the parasite from the human host to the Anopheles vector. We conducted...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20305663
DOI: 10.1038/ng.554

Genes

HBB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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