Article
ATM variants and cancer risk in breast cancer patients from Southern Finland.
BMC cancer - 16 Aug 2006
Tommiska Johanna, Jansen Laila, Kilpivaara Outi, Edvardsen Hege, Kristensen Vessela, Tamminen Anitta, Aittomäki Kristiina, Blomqvist Carl, Børresen-Dale Anne-Lise, Nevanlinna Heli
Abstract excerpt
BACKGROUND: Individuals heterozygous for germline ATM mutations have been reported to have an increased risk for breast cancer but the role for ATM genetic variants for breast cancer risk has remained unclear. Recently, a common ATM variant, ATMivs38 -8T>C in cis with the ATMex39 5557G>A (D1853N) variant, was suggested to associate with bilateral breast cancer among familial breast cancer patients from Northern...
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