Article
Recent advances in quantitative chimerism analysis.
Expert review of molecular diagnostics - 1 Nov 2009
Gineikiene Egle, Stoskus Mindaugas, Griskevicius Laimonas
Abstract excerpt
Quantitative chimerism analysis is a diagnostic tool used to monitor engraftment kinetics after allogeneic stem cell transplantation. It reflects the proportion of recipient and donor genotypes and is based on the identification of genetic markers characteristic to a given transplant pair. Currently, PCR amplification of short tandem repeats and single-nucleotide polymorphism-specific quantitative real-time PCR...
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