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Article

A strategy for single nucleotide polymorphism analysis of chimerism for somatic cell therapy.

Cytotherapy - 1 Dec 2010

Chen Xiaohua, Hofmann Ted J, Otsuru Satoru, Jethva Reena, Lind Curt, Monos Dimitri, Horwitz Edwin M

Abstract excerpt

BACKGROUND AIMS: Chimerism is an important outcome measure in hematopoietic cell transplantation as well as somatic cell therapy. Commonly used methods to estimate chimerism are restricted by either gender or inefficient sensitivity. In principle, real-time polymerase chain reaction (PCR)-based assays can be used to assess single nucleotide polymorphisms (SNP), which are a vast resource of molecular markers, and...

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PMID: 20429790
DOI: 10.3109/14653241003774029

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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