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Article

New methods for the quantification of mixed chimerism in transplantation

19 Jan 2023

Abstract excerpt

Background Quantification of chimerism showing the proportion of the donor in a recipient is essential for the follow-up of hematopoietic stem cell transplantation but can also be useful to document an immune tolerance situation after solid organ transplantation. Historically, chimerism has been quantified from genomic DNA, but with technological advances, chimerism from donor-derived cell-free DNA seems...

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PMID: 36742303
DOI: 10.3389/fimmu.2023.1023116

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