Article
Highly sensitive patient-specific real-time PCR SNP assay for chimerism monitoring after allogeneic stem cell transplantation.
Laboratory hematology : official publication of the International Society for Laboratory Hematology - 1 Jan 2006
Eshel Rinat, Vainas Oded, Shpringer Meirav, Naparstek Elizabeth
Abstract excerpt
Chimerism analysis after allogeneic stem cell transplantation (allo-SCT) is an important diagnostic tool for the documentation of engraftment, early detection of graft failure, and recurrence of the disease. Current assays rely on the genetic polymorphism between the donor and the recipient, and allow semiquantitative or quantitative analysis of chimerism. The most common method in use is based on the...
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