Article
Regulatory Macrophages Inhibit Alternative Macrophage Activation and Attenuate Pathology Associated with Fibrosis.
Journal of immunology (Baltimore, Md. : 1950) - 15 Oct 2019
Chandrasekaran Prabha, Izadjoo Salman, Stimely Jessica, Palaniyandi Senthilkumar, Zhu Xiaoping, Tafuri Wagner, Mosser David M
Abstract excerpt
Diversity and plasticity are the hallmarks of macrophages. The two most well-defined macrophage subsets are the classically activated macrophages (CAMϕs) and the IL-4-derived alternatively activated macrophages (AAMϕs). Through a series of studies, we previously identified and characterized a distinct population of macrophages with immunoregulatory functions, collectively termed regulatory macrophages (RMϕs)....
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