Article
Failed renoprotection by alternatively activated bone marrow macrophages is due to a proliferation-dependent phenotype switch in vivo.
Kidney international - 1 Apr 2014
Cao Qi, Wang Yiping, Zheng Dong, Sun Yan, Wang Changqi, Wang Xin M, Lee Vincent W S, Wang Ya, Zheng Guoping, Tan Thian K, Wang Yuan M, Alexander Stephen I, Harris David C H
Abstract excerpt
Alternatively activated macrophages (M2) regulate immune responses and ex vivo polarized splenic M2 are able to ameliorate renal injury including models of renal disease, such as adriamycin nephropathy. Whether M2 derived from other organs have similar protective efficacy is unknown. Here, we rep...
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