Article
Peptide binding to empty HLA-B27 molecules of viable human cells.
Nature - 2 May 1991
Benjamin R J, Madrigal J A, Parham P
Abstract excerpt
Intracellular binding of antigenic peptides by polymorphic class I major histocompatibility complex molecules creates the ligands recognized by receptors of CD8+ T cells. Previously described in vitro assays of peptide binding to class I molecules have been limited by either the low proportion of...
Topics
- Alleles
- Amino Acid Sequence
- Antibodies, Monoclonal
- B-Lymphocytes
- Binding, Competitive
- Cell Line
- HLA-B27 Antigen
- Humans
- Kinetics
- Molecular Sequence Data
- Peptides
- Protein Binding
- T-Lymphocytes
- Transfection