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Article

HLA‐B27 modulates intracellular survival of <i>Salmonella enteritidis</i> in human monocytic cells

1 Jun 1997

Abstract excerpt

Human major histocompatibility complex class I allele HLA-B27 is associated with a group of diseases called spondyloarthropathies. In reactive arthritis (ReA), the disease is triggered by certain infections, e.g. gastroenteritis caused by Salmonella. The host/microbe interaction is abnormal in susceptible individuals leading to inefficient elimination of arthritis-triggering bacteria, fragments of them, or both,...

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Identifiers

PMID: 9209481
DOI: 10.1002/eji.1830270606

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

HLA‐B27 modulates intracellular survival of <i>Salmonella enteritidis</i> in human monocytic cellsPMID 9209481Read ↗

Enhanced intracellular replication of Salmonella enteritidis in HLA-B27-expressing human monocytic cells: dependency on glutamic acid at position 45 in the B pocket of HLA-B27.Semantic proximity Read ↗

HLA-B27 modulates intracellular growth of Salmonella pathogenicity island 2 mutants and production of cytokines in infected monocytic U937 cells.Semantic proximity Read ↗

Salmonella exploits HLA-B27 and host unfolded protein responses to promote intracellular replicationSemantic proximity Read ↗

HLA molecules, bacteria and autoimmunitySemantic proximity Read ↗

Modification of disease outcome in Salmonella-infected patients by HLA-B27Semantic proximity Read ↗

Inhibition of cell surface MHC class II expression by <i>Salmonella</i>Semantic proximity Read ↗

Lymphoblastoid cells express HLA‐B27 homodimers both intracellularly and at the cell surface following endosomal recyclingSemantic proximity Read ↗

Common Intra-Articular T Cell Expansions in Patients with Reactive Arthritis: Identical β-Chain Junctional Sequences and Cytotoxicity Toward HLA-B27Semantic proximity Read ↗

HLA-B27 expression and reactive arthritis susceptibility in two patient cohorts infected with Salmonella Typhimurium.Semantic proximity Read ↗

Peptide binding to empty HLA-B27 molecules of viable human cells.Semantic proximity Read ↗

Role of enterobacteria and HLA-B27 in spondyloarthropathies: studies with transgenic mice.Semantic proximity Read ↗

HLA‐B27‐Restricted Cytotoxic T Lymphocyte Responses to Arthritogenic Enterobacteria or Self‐Antigens are Dominated by Closely Related TCRBV Gene Segments. A Study in Patients with Reactive ArthritisSemantic proximity Read ↗

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