Article
The role of NK cells in the regulation of experimental metastasis in a murine lymphoma system.
Journal of leukocyte biology - 1 Jun 1991
Smithson G, Bittick T H, Chervenak R, Lee S J, Wolcott R M
Abstract excerpt
This report describes the role of natural killer (NK) cells in regulating the localization of two closely related murine lymphomas (ASL1 and ASL1w) to various organ sites. These tumors are phenotypically similar yet differ in their overall malignancy and experimental metastatic pattern. Both tumors show similar patterns of migration in kinetic studies, however, they vary in their NK susceptibility. Cold target...
Topics
- Animals
- Cell Survival
- Immunosuppression Therapy
- Killer Cells, Natural
- Liver Neoplasms
- Lymphocyte Depletion
- Lymphoma
- Male
- Mice
- Neoplasm Metastasis
- Phenotype
