NK cells from mammary tumor bearing mice do not exert natural killer activity but function as antibody dependent cellular cytotoxicity effectors.

Article

NK cells from mammary tumor bearing mice do not exert natural killer activity but function as antibody dependent cellular cytotoxicity effectors.

Anticancer research - 1 Jan 2000

Rivera L M, Lopez D M

Abstract excerpt

We have previously found that natural killer (NK) activity is profoundly decreased in BALB/c mice bearing large mammary tumors. Kinetic studies showed that after 14 days of tumor implantation a reduction of 25-40% of NK cytotoxicity can be observed and by 21 days only very low levels of NK reacti...

Topics

Animals
Antibody-Dependent Cell Cytotoxicity
Female
Killer Cells, Natural
Male
Mammary Neoplasms, Experimental
Mice
Mice, Inbred BALB C
Neoplasm Transplantation
Phenotype
Receptors, Fc
Spleen

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