Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dose effect of cigarette smoking on frequency and spectrum of epidermal growth factor receptor gene mutations in Korean patients with non-small cell lung cancer.

Journal of cancer research and clinical oncology - 1 Dec 2010

Lee Young Joo, Shim Hyo Sub, Kang Young Ae, Hong Su Jung, Kim Hyun Ki, Kim Hoguen, Kim Se Kyu, Choi Sung Ho, Kim Joo-Hang, Cho Byoung Chul

Abstract excerpt

PURPOSE: This study aimed to determine the dose effect of smoking on the mutational frequency and spectrum of epidermal growth factor receptor (EGFR) gene in Korean non-small cell lung cancer (NSCLC). METHODS: Detailed smoking histories were obtained from 324 consecutively enrolled Korean NSCLC patients. Mutational status of EGFR (exon 18-21) was determined using nested polymerase chain reaction amplification....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to Carcinoma, Non-Small-Cell Lung

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to ErbB Receptors

Share to Logistic Models

Share to Lung Neoplasms

Share to Smoking

Source

Identifiers

PMID: 20237940
DOI: 10.1007/s00432-010-0853-4

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dose effect of cigarette smoking on frequency and spectrum of epidermal growth factor receptor gene mutations in Korean patients with non-small cell lung cancer.PMID 20237940Read ↗

Impact of smoking status and pathologic type on epidermal growth factor receptor mutations in lung cancer.Semantic proximity Read ↗

Divergent epidermal growth factor receptor mutation patterns between smokers and non-smokers with lung adenocarcinoma.Semantic proximity Read ↗

Use of cigarette-smoking history to estimate the likelihood of mutations in epidermal growth factor receptor gene exons 19 and 21 in lung adenocarcinomas.Semantic proximity Read ↗

Impact of environmental tobacco smoke on the incidence of mutations in epidermal growth factor receptor gene in never-smoker patients with non-small-cell lung cancer.Semantic proximity Read ↗

The Impact of Sex and Smoking Status on the Mutational Spectrum of Epidermal Growth Factor Receptor Gene in Non–small Cell Lung CancerSemantic proximity Read ↗

Cumulative smoking dose affects the clinical outcomes of EGFR-mutated lung adenocarcinoma patients treated with EGFR-TKIs: a retrospective study.Semantic proximity Read ↗

Mutations within the tyrosine kinase domain of EGFR gene specifically occur in lung adenocarcinoma patients with a low exposure of tobacco smokingSemantic proximity Read ↗

Usefulness of cumulative smoking dose for identifying the EGFR mutation and patients with non-small-cell lung cancer for gefitinib treatment.Semantic proximity Read ↗

Frequency of well-identified oncogenic driver mutations in lung adenocarcinoma of smokers varies with histological subtypes and graduated smoking dose.Semantic proximity Read ↗

The role of mutation status of the epidermal growth factor receptor gene in advanced non-small cell lung cancer.Semantic proximity Read ↗

The impact of cigarette smoking on the frequency of and qualitative differences in KRAS mutations in Korean patients with lung adenocarcinoma.Semantic proximity Read ↗

[Analysis of EGFR mutations in 176 cases of non-small cell lung cancer].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.