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Article

Frequency of well-identified oncogenic driver mutations in lung adenocarcinoma of smokers varies with histological subtypes and graduated smoking dose.

Lung cancer (Amsterdam, Netherlands) - 1 Jan 2013

Li Hang, Pan Yunjian, Li Yuan, Li Chenguang, Wang Rui, Hu Haichuan, Zhang Yang, Ye Ting, Wang Lei, Shen Lei, Sun Yihua, Chen Haiquan

Abstract excerpt

PURPOSE: We performed this analysis to reveal the association between six well-identified oncogenic driver mutations and clinical and pathological features in lung adenocarcinomas from smokers. It may have the potentiality to optimize existing treatment strategies and clinical trial design. METHODS: In this series, 230 resected lung adenocarcinomas from smoker (>100 cigarettes in lifetime) at single center...

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Source

Identifiers

PMID: 23098378
DOI: 10.1016/j.lungcan.2012.09.018

Genes

EGFR
KRAS
ALK
BRAF
EML4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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