Article
Usefulness of cumulative smoking dose for identifying the EGFR mutation and patients with non-small-cell lung cancer for gefitinib treatment.
Cancer science - 1 Oct 2009
Jida Masaru, Toyooka Shinichi, Mitsudomi Tetsuya, Takano Toshimi, Matsuo Keitaro, Hotta Katsuyuki, Tsukuda Kazunori, Kubo Takafumi, Yamamoto Hiromasa, Yamane Masaomi, Oto Takahiro, Sano Yoshifumi, Kiura Katsuyuki, Yatabe Yasushi, Ohe Yuichiro, Date Hiroshi, Miyoshi Shinichiro
Abstract excerpt
We examined the diagnostic accuracy of the cumulative smoking dose for identifying the epidermal growth factor receptor (EGFR) exon 19 deletion and L858R mutation among Japanese patients with non-small-cell lung cancer (NSCLC). EGFR mutations in exon 19 and exon 21 were determined in 1001 NSCLC p...
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