Repeated exposure of Candida spp. to miconazole demonstrates no development of resistance.

doi:10.1111/j.1439-0507.2010.01867.x

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Article

Repeated exposure of Candida spp. to miconazole demonstrates no development of resistance.

Mycoses - 1 Jul 2011

Ghannoum M A, Herbert J, Isham N

Abstract excerpt

Oropharyngeal candidiasis (OPC) is a common infection among the immuno-compromised population. Treatments include both systemic azoles, most commonly fluconazole (FLU), and topical agents such as miconazole (MICON). However, resistance to FLU has been reported with a greater frequency. The aim of this study was to determine the potential for development of resistance following repeated exposure of Candida spp. to...

Topics

Candida albicans
Candida glabrata
Candida tropicalis
Candidiasis
Drug Resistance, Fungal
Humans
Miconazole
Microbial Sensitivity Tests
Mutation
Serial Passage

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Identifiers

PMID: 20236241
DOI: 10.1111/j.1439-0507.2010.01867.x
PMCID: PMC2955168

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