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Article

Multiple resistant phenotypes of Candida albicans coexist during episodes of oropharyngeal candidiasis in human immunodeficiency virus-infected patients.

Antimicrobial agents and chemotherapy - 1 Jul 1999

Lopez-Ribot J L, McAtee R K, Perea S, Kirkpatrick W R, Rinaldi M G, Patterson T F

Abstract excerpt

Mechanisms of resistance to azoles in Candida albicans, the main etiologic agent of oropharyngeal candidiasis (OPC), include alterations in the target enzyme (lanosterol demethylase) and increased efflux of drug. Previous studies on mechanisms of resistance have been limited by the fact that only a single isolate from each OPC episode was available for study. Multiple isolates from each OPC episode were evaluated...

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Source

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Identifiers

PMID: 10390213
DOI: 10.1128/AAC.43.7.1621
PMCID: PMC89334

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Source receipt: pubmed, retrieved 7 Sept 2026.

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