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Article

Cross-Resistance of clinical isolates of Candida albicans and Candida glabrata to over-the-counter azoles used in the treatment of vaginitis.

Microbial drug resistance (Larchmont, N.Y.) - 1 Jan 2000

Cross E W, Park S, Perlin D S

Abstract excerpt

Antifungal drug resistance in Candida spp. continues to increase in response to the widespread application of triazole therapeutics among immunosuppressed patients. Azole-based over-the-counter (OTC) antifungal agents used to treat vaginitis have the potential to exacerbate this problem by contributing to the selection of highly resistant strains of Candida in otherwise healthy women. In this study, we show that...

Topics

Antifungal Agents
Azoles
Candida
Candida albicans
Candidiasis
Candidiasis, Vulvovaginal
Drug Resistance, Microbial
Female
Fungemia
Humans
Immunocompromised Host

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Microbial Sensitivity Tests

Mutation

Neoplasms

Nonprescription Drugs

Source

Identifiers

PMID: 10990271
DOI: 10.1089/107662900419474

Genes

OTC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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