Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human Lymphoblastoid Cell Line Panels: Novel Tools for Assessing Shared Drug Pathways

1 Mar 2010

Abstract excerpt

AIMS: While powerful in silico tools are emerging for predicting drug targets and pathways, general in vitro tools for assessing such predictions are lacking. We present a novel in vitro method for distinguishing shared versus distinct drug pathways based on comparative cell growth inhibition profiles across a small panel of human lymphoblastoid cell lines (LCLs) from individual donors. MATERIALS & METHODS: LCLs...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Lymphoblastic Leukemia research
Share to Cancer Cells and Metastasis
Share to Cancer, Stress, Anesthesia, and Immune Response

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20235789
DOI: 10.2217/pgs.10.27

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human Lymphoblastoid Cell Line Panels: Novel Tools for Assessing Shared Drug PathwaysPMID 20235789Read ↗

Heritable and non-genetic factors as variables of pharmacologic phenotypes in lymphoblastoid cell lines.Semantic proximity Read ↗

Lymphoblastoid cell lines models of drug response: successes and lessons from this pharmacogenomic model.Semantic proximity Read ↗

Genome-wide Expression Profiling of Human Lymphoblastoid Cell Lines Identifies CHL1 as a Putative SSRI Antidepressant Response BiomarkerSemantic proximity Read ↗

Lymphoblastoid Cell Lines in Pharmacogenomic Discovery and Clinical TranslationSemantic proximity Read ↗

Use of cell lines in the investigation of pharmacogenetic loci.Semantic proximity Read ↗

Aggregated Compound Biological Signatures Facilitate Phenotypic Drug Discovery and Target Elucidation.Semantic proximity Read ↗

Multidimensional drug profiling by automated microscopy.Semantic proximity Read ↗

Profiling of drugs and environmental chemicals for functional impairment of neural crest migration in a novel stem cell-based test batterySemantic proximity Read ↗

Genome-wide association and pharmacological profiling of 29 anticancer agents using lymphoblastoid cell lines.Semantic proximity Read ↗

Systems Pharmacology Dissection of Cholesterol Regulation Reveals Determinants of Large Pharmacodynamic Variability between Cell Lines.Semantic proximity Read ↗

Lithium-responsive genes and gene networks in bipolar disorder patient-derived lymphoblastoid cell lines.Semantic proximity Read ↗

Integrative genomic strategies applied to a lymphoblast cell line model reveal specific transcriptomic signatures associated with clozapine responseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.