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Article

Haplotypes of the adrenergic system predict the blood pressure response to beta-blockers in women with essential hypertension.

Pharmacogenomics - 1 Mar 2010

Filigheddu Fabiana, Argiolas Giuseppe, Degortes Simona, Zaninello Roberta, Frau Francesca, Pitzoi Silvia, Bulla Emanuela, Bulla Patrizia, Troffa Chiara, Glorioso Nicola

Abstract excerpt

AIMS: To analyze the association of haplotypes of the adrenergic system with essential hypertension and with the blood pressure response to beta-blockers. MATERIALS & METHODS: In 1112 never-treated essential hypertension patients and 203 normotensive controls, tightly linked SNPs of beta-adrenergic receptors (ADRB1 - Ser49Gly and Arg389Gly; ADRB2 - Cys19Arg, Gly16Arg and Gln27Glu) and the G-protein beta3-subunit...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20235788
DOI: 10.2217/pgs.09.158

Genes

GNB3
ADRB1
ADRB2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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