Article
Haplotypes of the beta2-adrenergic receptor gene are associated with essential hypertension in a Singaporean Chinese population.
Journal of hypertension - 1 Nov 2004
Lee Yee-Wei, Oh Vernon M S, Garcia Edwin, Taylor Elizabeth A, Wu Huimin, Yap Eric Ph, Kazeem Gbenga R, Caulfield Mark J, Munroe Patricia B
Abstract excerpt
OBJECTIVE: To investigate the relation between the gene encoding the beta2-adrenergic receptor (B2AR) and essential hypertension in a Singaporean Chinese cohort. METHODS: Three single nucleotide polymorphisms (SNPs) were genotyped in 190 cases and 323 controls, and eight haplotypes were determined and tested for association using the likelihood test statistic. RESULTS: We observed a significant difference in...
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