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Article

Interferon-lambda genotype and low serum low-density lipoprotein cholesterol levels in patients with chronic hepatitis C infection.

Hepatology (Baltimore, Md.) - 1 Jun 2010

Li Josephine H, Lao Xiang Qian, Tillmann Hans L, Rowell Jennifer, Patel Keyur, Thompson Alexander, Suchindran Sunil, Muir Andrew J, Guyton John R, Gardner Stephen D, McHutchison John G, McCarthy Jeanette J

Abstract excerpt

UNLABELLED: Recently, genetic polymorphisms occurring in the interferon (IFN)-lambda gene region were associated with response to IFN-based treatment of hepatitis C infection. Both infection with the hepatitis C virus and IFN therapy are associated with decreased serum cholesterol and high cholesterol has been associated with increased likelihood to respond to IFN. We sought to determine if the IFN-lambda gene...

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Share to Cholesterol, LDL
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Hepatitis C, Chronic

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Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 20235331
DOI: 10.1002/hep.23592
PMCID: PMC2921623

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