Cognitive state and connectivity effects of the genome-wide significant psychosis variant in ZNF804A.

doi:10.1016/j.neuroimage.2010.10.012

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Article

Cognitive state and connectivity effects of the genome-wide significant psychosis variant in ZNF804A.

NeuroImage - 1 Feb 2011

Esslinger Christine, Kirsch Peter, Haddad Leila, Mier Daniela, Sauer Carina, Erk Susanne, Schnell Knut, Arnold Claudia, Witt Stephanie H, Rietschel Marcella, Cichon Sven, Walter Henrik, Meyer-Lindenberg Andreas

Abstract excerpt

Alterations of connectivity are central to the systems-level pathophysiology of schizophrenia. One of the best-established genome-wide significant risk variants for this highly heritable disorder, the rs1344706 single nucleotide polymorphism in ZNF804A, was recently shown to modulate connectivity in healthy carriers during working memory (WM) in a pattern mirroring that which was found in overt disease. However,...

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PMID: 20946959
DOI: 10.1016/j.neuroimage.2010.10.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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