Article
Effect of 5-HT1A-receptor functional polymorphism on Theory of Mind performances in schizophrenia.
Psychiatry research - 30 Jul 2011
Bosia Marta, Anselmetti Simona, Bechi Margherita, Lorenzi Cristina, Pirovano Adele, Cocchi Federica, Buonocore Mariachiara, Bramanti Placido, Smeraldi Enrico, Cavallaro Roberto
Abstract excerpt
Theory of Mind (ToM) abilities are known to be impaired in schizophrenia and data from functional brain imaging studies showed that ToM deficit is correlated to prefrontal cortex (PFC) dysfunction. Moreover, several lines of evidence suggest a critical role for dopaminergic-serotoninergic interactions at the PFC level. In this view, we aimed to analyse the specific effect of the -1019C/G functional polymorphism...
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