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Article

Dendritic cell responses to Plasmodium falciparum in a malaria-endemic setting.

Malaria journal - 6 Jan 2021

Turner Triniti C, Arama Charles, Ongoiba Aissata, Doumbo Safiatou, Doumtabé Didier, Kayentao Kassoum, Skinner Jeff, Li Shanping, Traore Boubacar, Crompton Peter D, Götz Anton

Abstract excerpt

BACKGROUND: Plasmodium falciparum causes the majority of malaria cases worldwide and children in sub-Saharan Africa are the most vulnerable group affected. Non-sterile clinical immunity that protects from symptoms develops slowly and is relatively short-lived. Moreover, current malaria vaccine candidates fail to induce durable high-level protection in endemic settings, possibly due to the immunomodulatory effects...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33407502
DOI: 10.1186/s12936-020-03533-w
PMCID: PMC7787131

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