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Article

Genetic variations in genes encoding RANK, RANKL, and OPG in rheumatoid arthritis: a case-control study.

The Journal of rheumatology - 1 May 2010

Assmann Gunter, Koenig Jochem, Pfreundschuh Michael, Epplen Joerg T, Kekow Joern, Roemer Klaus, Wieczorek Stefan

Abstract excerpt

OBJECTIVE: Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic inflammation of the joints, which may lead to structural damage of the cartilage and bone. The receptor activator of nuclear factor-kappaB (RANK) and the osteoprotegerin (OPG) cascade system have been reported to be essential in osteoclastogenesis. Genetic variations in the genes coding for RANK, RANK ligand (RANKL),...

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Source

Identifiers

PMID: 20231205
DOI: 10.3899/jrheum.091110

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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