Article
Polymorphisms within the RANK and RANKL Encoding Genes in Patients with Rheumatoid Arthritis: Association with Disease Progression and Effectiveness of the Biological Treatment.
Archivum immunologiae et therapiae experimentalis - 19 Aug 2020
Wielińska Joanna, Kolossa Katarzyna, Świerkot Jerzy, Dratwa Marta, Iwaszko Milena, Bugaj Bartosz, Wysoczańska Barbara, Chaszczewska-Markowska Monika, Jeka Sławomir, Bogunia-Kubik Katarzyna
Abstract excerpt
Inconsistency of the results regarding the genetic variability within genes coding for receptor activator of nuclear factor κB (RANK) and its ligand (RANKL) in rheumatoid arthritis (RA) prompted us to study the RANK and RANKL polymorphisms as potential biomarkers associated with disease predisposition and response to anti-TNF treatment in a group of Polish patients with RA. This study enrolled 318 RA patients and...
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