Article
Single nucleotide polymorphism of RANKL and OPG genes may play a role in bone and joint injury in rheumatoid arthritis.
Clinical and experimental rheumatology - 1 Jan 2000
Xu Shengqian, Ma Xi-Xi, Hu Lin-Wei, Peng Li-Ping, Pan Fa-Ming, Xu Jian-Hua
Abstract excerpt
OBJECTIVES: This paper aims to investigate the influence of single-nucleotide polymorphisms (SNPs) in the receptor of activator of nuclear factor kappaB ligand (RANKL) gene (TNFSF11) and osteoprotegerin (OPG) gene (TNFRSF11B) on bone and joint injury in patients with rheumatoid arthritis (RA). METHODS: Two hundred RA patients and 201 matched controls were analysed by case-control design, and their samples were...
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