Article
[The role of cholesterol in Alzheimer's neuro-pathogenesis].
Rivista di biologia - 1 Jan 2000
Biondi Elisa
Abstract excerpt
Alzheimer's Disease (AD) is the most common neurodegenerative disorder in western societies affecting up to 15 million individuals worldwide.It leads to death after a progressive memory deficit and cognitive impairment accompanied by the appearance of two pathological hallmarks in specific brain areas: neurofibrillary tangles and amyloid plaques. Cholesterol homeostasis may play a key role in AD pathogenesis and...
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