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Article

Investigating a new generation of ribozymes in order to target HCV.

PloS one - 10 Mar 2010

Lévesque Michel V, Lévesque Dominique, Brière Francis P, Perreault Jean-Pierre

Abstract excerpt

For a long time nucleic acid-based approaches directed towards controlling the propagation of Hepatitis C Virus (HCV) have been considered to possess high potential. Towards this end, ribozymes (i.e. RNA enzymes) that specifically recognize and subsequently catalyze the cleavage of their RNA substrate present an attractive molecular tool. Here, the unique properties of a new generation of ribozymes are taken...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20224783
DOI: 10.1371/journal.pone.0009627
PMCID: PMC2835756

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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