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Article

An ELISA for RNA helicase activity: application as an assay of the NS3 helicase of hepatitis C virus.

Biochemical and biophysical research communications - 30 Dec 1998

Hsu C C, Hwang L H, Huang Y W, Chi W K, Chu Y D, Chen D S

Abstract excerpt

A convenient enzyme-linked immunosorbent assay (ELISA) for RNA helicase activity was developed with principles similar to the standard assay. The helicase ELISA utilizes a non-radioactive double-stranded substrate with a biotin-labeled template (long) strand hybridized to a digoxigenin (DIG)-labe...

Topics

Catalytic Domain
Enzyme-Linked Immunosorbent Assay
Hepacivirus
Mutation
Potassium Chloride
RNA Helicases
Viral Nonstructural Proteins
Viral Proteins

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 9918773
DOI: 10.1006/bbrc.1998.9813

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9918773-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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