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Article

Establishment of a new quantitative detection approach to adefovir-resistant HBV and its clinical application.

World journal of gastroenterology - 14 Mar 2010

Zhao Wei-Feng, Shao You-Lin, Chen Liang-Yun, Wu Jin-Hua, Zhu Yi-Ling, Gan Jian-He, Xiong Hui

Abstract excerpt

AIM: To establish the more feasible and sensitive assessment approach to the detection of adefovir (ADV) resistance-associated hepatitis B virus (HBV) quasispecies. METHODS: Based on the characteristics of rtA181V/T and rtN236T mutations, a new approach based on real-time fluorescent quantitative polymerase chain reaction (RT-PCR) was established for the detection of ADV-resistant HBV quasispecies, total HBV DNA,...

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Identifiers

PMID: 20222172
DOI: 10.3748/wjg.v16.i10.1267
PMCID: PMC2839181

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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