Article
[Dissection of mechanism for the adefovir dipivoxil resistance in chronic hepatitis B patients].
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology - 1 Oct 2009
Zeng Ai-Zhong, Lu Ping, Deng Hui, Cai Su-Fang, Yang Chun, Xin Xiao-Juan, Guo Jin-Jun, Li Qing-Ling, Deng Xiao-Hui, Huang Ai-Long
Abstract excerpt
OBJECTIVE: To explore the mechanism for adefovir dipivoxil (ADV) resistance occurred in chronic hepatitis B patients of a series of phase III clinical trails. METHODS: 30 resistant HBV strains were selected out from 177 cases of ADV treated chronic hepatitis B patients. HBV polymerase RT region w...
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