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Article

The rtA181S mutation of hepatitis B virus primarily confers resistance to adefovir dipivoxil.

Journal of viral hepatitis - 1 Mar 2015

Liu Y, Li X, Xin S, Xu Z, Chen R, Yang J, Liu L, Wong V W-S, Yang D, Chan H L-Y, Xu D

Abstract excerpt

The study aimed to clarify clinical significance of hepatitis B virus (HBV) rtA181S mutation in Chinese HBV-infected patients. A total of 18 419 patients with chronic HBV infection from Beijing 302 Hospital were investigated. HBV complete reverse transcriptase region of polymerase was screened by direct sequencing, and the results were verified by clonal sequencing. Replication-competent mutant and wild-type HBV...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25132017
DOI: 10.1111/jvh.12298

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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