Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Macrophage migration inhibitory factor-knockout mice are long lived and respond to caloric restriction.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Jul 2010

Harper James M, Wilkinson J Erby, Miller Richard A

Abstract excerpt

Macrophage migration inhibitory factor (MIF) affects inflammation, glucose homeostasis, and cellular proliferation in mammals. Previously, we found that MIF was significantly elevated in multiple long-lived mouse models, including calorie restriction (CR), which led us to hypothesize that MIF mig...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amyloidosis
Share to Body Weight
Share to Caloric Restriction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glomerulonephritis

Share to Hemangiosarcoma

Share to Inflammation

Share to Longevity

Share to Macrophage Migration-Inhibitory Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 20219983
DOI: 10.1096/fj.09-152223
PMCID: PMC2887269

Genes

MIF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20219983-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Macrophage migration inhibitory factor-knockout mice are long lived and respond to caloric restriction.PMID 20219983Read ↗

Temporal linkage between the phenotypic and genomic responses to caloric restriction.Semantic proximity Read ↗

Selenium supplementation inhibits IGF-1 signaling and confers methionine restriction-like healthspan benefits to miceSemantic proximity Read ↗

Life extension in the dwarf mouse.Semantic proximity Read ↗

Methionine restriction restores a younger metabolic phenotype in adult mice with alterations in fibroblast growth factor 21.Semantic proximity Read ↗

Link between aging and atheroprotection in <i>Mif</i> -deficient atherosclerotic miceSemantic proximity Read ↗

GH and IGF1: roles in energy metabolism of long-living GH mutant mice.Semantic proximity Read ↗

Dietary restriction impacts health and lifespan of genetically diverse mice.Semantic proximity Read ↗

Longevity effect of IGF-1R(+/-) mutation depends on genetic background-specific receptor activation.Semantic proximity Read ↗

The p53-dependent effects of macrophage migration inhibitory factor revealed by gene targeting.Semantic proximity Read ↗

Mice producing reduced levels of insulin-like growth factor type 1 display an increase in maximum, but not mean, life span.Semantic proximity Read ↗

The longevity effects of reduced IGF-1 signaling depend on the stability of the mitochondrial genome.Semantic proximity Read ↗

The longevity effects of reduced IGF-1 signaling depend on the stability of the mitochondrial genomeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.