Article
Life extension in the dwarf mouse.
Current topics in developmental biology - 1 Jan 2004
Bartke Andrzej, Brown-Borg Holly
Abstract excerpt
Ames dwarf mice and Snell dwarf mice lack growth hormone (GH), prolactin (PRL), and thyroid-stimulating hormone (TSH), live much longer than their normal siblings, and exhibit many symptoms of delayed aging. "Laron dwarf mice," produced by targeted disruption of the GH receptor/GH-binding protein...
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